龔紘毅
張清風
周信佑
呂明偉
林正輝
陸振岡
吳貫忠
陳榮祥
黃章文
邱品文
廖柏凱
專任助教
約聘助教
 
龔紘毅 (Hong-Yi Gong, Ph.D.)
職稱: 副教授兼系主任
( Associate Professor & Chairman)
學歷: 國防醫學院生命科學研究所博士
( Ph.D., Graduate Institute of Life Sciences, National Defense Medical Center, Taiwan, R.O.C. )
專長: 分子遺傳學、海洋生物技術、分子細胞生物學
( Molecular Genetics、Marine Biotechnology、Molecular Cell Biology )
電話: 02-2462-2192 轉分機 5224
Email: hygong@mail.ntou.edu.tw
網址: http://lms.ls.ntou.edu.tw/hygong
Refereed Papers
Lin, L. Y., Chiang, C. C., Gong, H. Y., Cheng, C. Y., Hwang, P. P. and Weng, C. F. (2003). Cellular Distributions of Creatine Kinase in Branchia of Euryhaline Tilapia (Oreochromis mossambicus). Am J Physiol Cell Physiol 284: C233–C241. (SCI)
Gong, H. Y., Lin, C. J. F., Chen, M. H. C., Hu, M. C., Lin, G. H., Zhou, Y., Zon, L. I., Wu, J. L. (2004). Two distinct teleost hepatocyte nuclear factor 1 genes, hnf1-alpha/tcf1 and hnf1-beta/tcf2, abundantly expressed in liver, pancreas, gut and kidney of zebrafish. Gene 338: 35-46. (SCI)
Lin, G. H., Chen, M. H. C., Gong, H. Y., Hsieh, D. J. Y., Lin, C. J. F., Wu, J. L. (2004). Functional analysis of insulin-like growth factor 1 receptor gene promoter in the zebrafish. Marine Biotechnology 6: S146-S152. (SCI)
Amali, A. A., Lin, C. J., Chen, Y. H., Wang, W. L., Gong, H. Y., Lee, C. Y., Ko, Y. L., Lu, J. K., Her, G. M., Chen, T. T., Wu, J. L. (2004). Up-regulation of muscle-specific transcription factors during embryonic somitogenesis of zebrafish (Danio rerio) by knock-down of myostatin-1. Dev. Dyn. 229: 847-56. (SCI)
Gong, H. Y., Wu, J. L., Huang, W. T., Lin, C. J. F., and Weng, C. F. (2004). Response to acute changes in salinity of two different muscle type creatine kinase isoforms, from euryhaline teleost (Oreochromis mossambicus) gills. Bioch. Biophy. Acta General Subjects 1675: 184-191. (SCI)
Chen, J. Y., Chou, M. J., Gong, H. Y., Huang, T. C., Wu, J. L. C.M. Kuo. (2005). Cloning and characterization of zebrafish (Danio rerio) insulin-like growth factor binding protein-2 proximal promoter region. DNA Cell Biol. 24: 199-208. (SCI)
Amali, A. A., Rekha, R. D., Lin, C. J. F., Wang, W. L., Gong, H. Y. , Her, G. M. and Wu, J. L. (2006). Thioacetamide induced liver damage in zebrafish embryo as a disease model for steatohepatitis. J. Biomedical Science 13: 225-232. (SCI)
Hu, S. Y., Huang, J. H., Huang, W. T., Yeh, Y. H., Chen, M. H. C., Gong, H. Y. , Chiou T. T., Yang, T. H., Chen, T. T., Lu, J. K. and Wu, J. L. (2006). Structure and function of antimicrobial peptide penaeidin-5 from the black tiger shrimp Penaeus monodon. Aquaculture 260: 61-68. (SCI)
Chen, M. H. C., Li, Y. H., Chang, Y., Hu, S. Y., Gong, H. Y. , Lin, G. H., Chen, T. T. and Wu, J. L. (2007). Co-induction of hepatic IGF-1 and progranulin mRNA by growth hormone in tilapia (Oreochromis mossambicus). General Comparative Endocrinology 150: 212-218. (SCI)
Hu, M. C.#, Gong, H. Y.#, Lin, G. H., Hu, S.Y., Chen, M. H. C., Huang, S. J., Liao, C. F. and Wu, J. L. (2007). XBP-1, a key regulator of unfolded protein response, activates transcription of IGF1 and Akt phosphorylation in zebrafish embryonic cell line. Biochem. Bioph. Res. Co. 359: 778-783. (SCI)
Huang, W. T., Yu, H. C., Hsu, C. C., Liao, C. F., Gong, H. Y., Lin, C. J. F., Wu, J. L., and Weng, C. F. (2007). Steroid hormones (17beta-estradiol and hydrocortisone) upregulate hepatocyte nuclear factor (HNF)-3beta and insulin-like growth factor I and II expression in the gonads of tilapia (Oreochromis mossambicus) in vitro. Theriogenology 68: 988-1002. (SCI)
Rekha, R. D., Amali, A. A., Her, G. M., Yeh, Y. H., Gong, H. Y., Hu, S. Y., Lin, G. H. and Wu, J. L. (2008). Thioacetamide accelerates steatohepatitis, cirrhosis and HCC by expressing HCV core protein in transgenic zebrafish Danio rerio. Toxicology 243: 11-22. (SCI)
Chou, M. C., Chen, J. C., Chen, J. Y., Gong, H. Y., Li, L. T., Huang, T. C., Wu, J. L. and Kuo, C. M. (2008). Isolation and characterization of the zebrafish (Danio rerio) insulin-like growth factor binding protein-3 promoter region. Fisheries Science 74: 153-166. (SCI)
Wu, H. C., Chiu, C. S., Wu, J. L., Gong, H. Y., Chen, M. C., Lu, M. W. and Hong, J. R. (2008). Zebrafish anti-apoptotic protein zfBcl-xL can block betanodavirus protein-alpha-induced mitochondria -mediated secondary necrosis cell death. Fish & Shellfish Immunology 24: 436-449. (SCI)
Amali, A. A., Lin, C. J., Chen, Y. H., Wang, W. L., Gong, H. Y., Rekha, R. D., Lu, J. K., Chen, T. T. and Wu, J. L. (2008). Overexpression of Myostatin2 in zebrafish reduces the expression of dystrophin associated protein complex (DAPC) leads to muscle dystrophy. J. Biomedical Science 15: 595-604. (SCI)
Lin, C. J. F., Gong, H. Y., Tseng, H. C., Wang, W. L., Wu, J. L. (2008). miR-122 targets an anti-apoptotic gene, Bcl-w, in human hepatocellular carcinoma cell lines. Biochem. Bioph. Res. Co. 375: 315-320. (SCI)
Hu, S. Y., Chen, M. H. C., Lin, Y. C., Lin, G. H., Gong, H. Y., Wu, J. L. (2008). Cloning and functional analysis of the proximal promoter region of the three GnRH genes from silver sea bream (Sparus sarba). Comp. Biochem. Physiol. B Biochem. Mol. Biol. 151: 373-380. (SCI)
Lee, C. Y., Hu, S. Y., Gong, H. Y., Chen, M.C., Lu, J. K., Wu, J. L. (2009). Suppression of myostatin with vector-based RNA interference causes a double-muscle effect in transgenic zebrafish. Biochem. Bioph. Res. Co. 387: 766-771. (SCI)
Hu, S. Y., Lin, P. Y., Liao, C. H., Gong, H. Y., Lin, G. H., Kawakami, K., Wu, J. L. (2010). Nitroreductase-mediated gonadal dysgenesis for infertility control of genetically modified zebrafish. Marine Biotechnology 12: 569-578. (SCI)
Hu, S. Y., Liao, C. H., Lin, I. P., Li, Y. H., Gong, H. Y., Lin, G. H., Kawakami, K., Yang, T. H., Wu, J. L. (2010). Zebrafish eggs used as bioreactors for the production of bioactive tilapia insulin-like growth factors. Transgenic Research 2010 Apr. 7 [Epub ahead of print] (in press) (SCI)
Li, Y. H., Chen, M. C. C., Gong, H. Y., Hu, S. Y., Li, Y. W., Lin, G. H., Lin, C. C., Liu, W. and Wu, J. L. (2010). Progranulin A-mediated MET signaling is essential for liver morphogenesis in zebrafish. J. Biol. Chem. 2010 Oct. 20 [Epub ahead of print] (in press) (SCI)